Session 4 – Cholinesterase pharmacology, inhibitors and antidotes
Chair and keynote lecturer: Palmer Taylor, San Diego (USA)
| Time | Lecture |
|---|---|
| 16:15 | Keynote Lecture: Palmer Taylor, San Diego (USA) Balancing Central and Peripheral Nervous System Antidotal Actions of Oxime Reactivators to Acetylcholinesterase Inhbition |
| 16:45 | Senior Lecture: Yvonne Rosenberg, Rockville (USA) Development of the post-exposure RS194B oxime against lethal sarin vapour and organophosphate insecticides in macaques |
| 17:05 | Senior Lecture (20 min): Anita Bosak, Zagreb (Croatia) Detection of selective inhibitors of BChE in structurally and functionally different groups of molecules |
| 17:25 | Senior Lecture (20 min): Lukas Gorecki (Czech Republic) Bifunctional compounds serving as versatile cholinesterase reactivators |
| 17:45 | Junior Lecture (10 min flash presentation): Nikolina Maček Hrvat (Croatia) Attenuating organophosphate-induced neuroinflammation in mice by oxime therapy |
| 17:55 | Junior Lecture (10 min flash presentation): Cecilia Springer Engdahl (Sweeden) Design and Evaluation of Acetylcholinesterase Reactivators: A study of reactive oxime- and peripheral site-moieties |