Session 7 – Multi-target-directed ligands in Alzheimer’s disease primarily targeting cholinesterases
Chair and keynote lecturer: Stanislav Gobec, Ljubljana (Slovenia)
Time | Lecture |
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10:45 | Keynote Lecture: Stanislav Gobec, Ljubljana (Slovenia) Multi-target-directed ligands for potential symptomatic and disease-modifying treatment of Alzheimer’s disease |
11:15 | Senior Lecture (20 min): Christophe Rochais, Caen (France) Advancing Neocopride: A Preclinical Candidate Multitarget Directed-Ligand (MTDL) for Neurodegenerative Disease Intervention |
11:35 | Senior Lecture (20 min): Jose Marco-Contelles, Madrid (Spain) Cholinesterase-based Inhibitors as Multitarget Small Molecules for the therapy of Alzheimer’s Disease |
11:55 | Senior Lecture (20 min): Haopeng Sun, Nanjing (China) Discovery of highly selective butyrylcholinesterase inhibitors for cognitive improvement |
12:15 | Junior Lecture (10 min flash presentation): Weronika Bagrowska (Poland) Development of dual pharmacophore models of acetylcholinesterase and human soluble epoxide hydrolase based on local co-solvent molecules distribution |
12:25 | Junior Lecture (10 min flash presentation): Anže Meden (Slovenia) Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer’s disease |